Not a chance!!
My old '63 C10 was a sleeper like that. I had 2 different configurations that I liked very well. The '65 corvette 327 with the '57 corvette dual quad high rise with dual Carter WCFBs. Paired with a TH400 and 3.73:1, that baby screamed, but like you noted before, no one really needs that kind of rpms in a truck. I made it to 135mph with that setup, but swore I would never, ever, do it again!!! Too fast for that chassis. The other was a small block 400 with the Holley 4165 650cfm spreadbore, the TH400, and the 3.73:1. More grunt, less top end. Topped out around 105mph or so, but got there really quick.
I don't know why I was even thinking about trying to revisit the high rpm monster 327 again. My '62 doesn't have any better suspension than the '63 did, and the aerodynamics are just as bad, if not worse. That was the big problem with the '63. As the speed increased, so did the airflow under the truck. It created an airfoil that lifted instead of squatted. High speed = high on the suspension and absolutely no room for error.
I think your Excalibur will have a lot better aerodynamics.