I have helped build an 11 sec. 1961 Chevy truck. Be prepared to not drive your truck for a while. We built a 350 chevy with a 6-71 blower. The engine made all the power we needed, but we could not get traction without tubbing the truck and putting a ladder bar suspension under it. Once we got the thing to hook, we could not keep transmissions in it. We tried several built TH350's, TH400's, and finally spent some bucks on a race built powerglide. This transmission has lasted for years.
Also, we ran 4.88 gears with 33" tall tires that were 21.5" wide.
My freind drove this truck to school almost everyday for 3 years. Now the truck has a 4-link, 498 cu.in. big block on three stages of nitrous. The truck runs low 9 sec. 1/4 mile times. Not bad for a truck that weighs close to 5000lbs.