A single 4 on an Offy or Clifford is about as outlandish as shorts in the summertime. It's been done for a long time, it's nothing new. You're not putting the 4 on a stock intake. You're putting it on a manifold that it was meant for. And as mentioned a couple posts up, you're secondaries on a 4 bbl are not opening all the time. You can even put tighter springs on 'em.
This setup is one of the easiest things to do for a very slight performance gain with easiest maintenance and driveability. You want more performance and a headache, install a 3x1 Offy. Deep pockets and ultimate performance, get fuel injected and a 12 port head.
Do what you want to do and experiment, it's your stuff. But you've got many years of experience (I don't include myself, still much learning to do) here telling you it's basically a waste of time and money.
If you're happy with the results, great. Would you probably be more happy modifying the stock intake or installing an Offy or Clifford? More than likely.
Or.... just install a different 1 bbl.


Tradin' up dimes for nickels...
'`'`'`'`'`'`
My \'65 Chevy C-20