Would the Rostra 250-4165 work for my VSS if I just use two of the magnets?
Nope.
If you read thru the VSS FAQ on the binderplanet(I assume that's where you got that part number) you will note the Rostra for RWD uses 1 magnet and for FWD vehicles it used 2 due to the gear reduction. But you will need to install and log data on your vehicle to verify.
But IMHO, depending on what you are paying for that one, you would be better off with the recommended JTR 2PRS VSS.
If you are also installing an aftermarket cruise control and it came with the Rostra pick up then I would run it. But if you are going to buy a VSS just for the EFI then go with the JTR unit.
HTH.