I think they have an external oil pump which is driven off of the front of the crankshaft. That would be their weak link I beleive. They're wider and heavier than a small block and more costly to rod. If you're dead set on using Buick, go with the 455, it's externally identical to the 350 but a whole lot more cubes,
Scott

Scott Ward

2 1948 1.5-ton Loadmasters
The red one and The snow pusher
1 1950 3100
1 1955.1 Chevy 6500
1 1954 Chevy 6500 2-Ton
1 1955 1st Series COE 5700
1 1963 K20 (454)
1 1964 C10 (350)
1 1951 1.5-ton Dump Truck
1953 and a 1956 Ford F800

Raising a teenager is like trying to nail Jello to a tree!