Hot Rod Dad;
I'm running a Pontiac 400 hooked up to my original SM420 in my '57 GMC. Not too hard to do. Just set it up like you would for a car,only drill out the lower tranny bolt holes in your BOP bellhousing and bolt the bellhousing to the tranny before you install the engine.Cut a plate big enough to reach almost to the stock crossmember where the original bellhousing was,Cut the center hole and drill your tranny mounting holes so it can fit between the tranny and the bellhousing,make a couple of angle brackets and fit them to the crossmember mounts. You can either bolt or weld them to your plate.You might have to build a piece of linkage to connect your clutch-I did,because my release fork was toast and I couldn't find a replacement on a Sunday,and had to drive to work the following Monday,so I used a clutch fork from a Camaro.If you use the old style iron fork you can use the stock linkage.
Frank50;
Same set up as the Pontiac 400,but you'll have to pull the crank and have the end drilled for a pilot bushing.You might end up having your flywheel balanced,I don't remember if the Caddy engines are internally balanced.
Speed