The NP241C will bolt directly to a 4L60e with no fuss. They were available for a couple years with a VSS from the factory, so you could get lucky.
A 2000-2002 Suburban will have a mechanical fan and cable throttle. An 03-06 will have an electronic throttle and (usually) an electric fan.
A 2000 will have an AIR pump and EGR. You can easily remove those in the tune, but you will have to get blockoff plates for them. The price difference for a slightly newer one that you don't have to mess with is negligible.
There are some differences in the wiring, the coils, and a couple other small changes between the 00-02 and 03-06, so you will want to keep track of what your donor was.
