Martin,
I have an Edelbrock carburetor on the Chevy 350 engine in my roadster street rod. It started life as a 1405. I added an electric choke and experimented with jets and metering rods to find a combination my engine likes. The jets came from a Carter "Strip Kit". Some of the metering rods came from that same "Strip Kit" and some came from Kragen Auto Parts, ordered from Edelbrock. That work was done in 2003. Since then I've adjusted the idle mixture screws twice, many years apart, following the exact procedure recommended in the manual that comes with those carburetors. Other than that the carburetor has not been touched.
It works well, yielding both power and fuel economy that seem very good.
I'm a geologist, not a mechanic, so this describes the results achieved by an amateur.