What you propose is certainly possible and I've seen a few successful examples.

Couple things to think about though:
With your newfound speed and power should you have better than original brakes too?
You'll need to have axle shafts modified to the correct length and splines to accommodate the old hubs and new differential side gears.
Cutting, lining up, and welding the parts back together and keeping a reasonably straight alignment is not an insignificant task.

If there was a newer axle that solved all those concerns and even has the correct bolt pattern would you use it?? (I would)
Here's a Tech Tip about swapping too that newer axle: http://www.stovebolt.com/techtips/bigbolts/p30swap/
These axles are cheap, no one really wants them probably because of the 10 lug pattern. I'd be willing to bet you can swap the entire axle cheaper and much faster than the cut and paste method.

Grigg


•1951 GMC 250 in the Project Journals
•1948 Chevrolet 6400 - Detroit Diesel 4-53T - Roadranger 10 speed overdrive - 4 wheel disc brakes
•1952 Chevrolet 3800 pickup
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"First, get a clear notion of what you desire to accomplish, and then in all probability you will succeed in doing it..." -Henry Maudslay-