I would use a stand alone computer and run the 454 TBI just for the ease of driveability. It will start right up, fast idle, idle down after warm up and not vapor lock when pushed hard. There's also the availablity and economics of parts that are available most everywhere for the 454's over the Caddy engine.
There's my opinion, but I may be a bit biased. I'm putting an '89 TBI 454 in my 54 COE one of these days, LOL,
Scott