Pedals are a problem, I had nothing to start with and never seen a truck before this one, so I don't know what stock should look like or how much clearance there really is. Using the bell housing Jim did may solve a lot of issues if it would bolt to your engine.
As far wheels go, that's something I know little about, I do know all the GM wheels changed when disk brakes came out. I used a kit from MASTER POWER BRAKES, which used the big GM rotors and single piston calipers from the A-body and F-body line of cars. The small metric calipers may have more clearance. Mine is a 5 on 4.75 bolt pattern. Artillery wheels would be pretty neat if you can make it work. Maybe cut out the centers and weld them in bigger hoops, now that would be cool.
There is room to get the later engine in if you set it back almost on the firewall then move the radiator forward and down. Mine has a mechanical fan, so moved the radiator quite a bit, if you had an electric pusher fan, you could save yourself about 3" of moving. I didn't fully understand the firewall issues when I made mine, I never would have recessed nearly as much as I did, the stock alcove would have been enough I think, but I was looking at the tall deck 292 at the time and knew I would need more hight.
As far as work goes, it would much easier to go with a full pressure 235, it would save a lot of fabricating.