Go back over the timing and vacuum advance unit just to be sure all is in order. Unhook the vacuum line to the distributor and plug the hose and go for a test drive.
Wheres the timing set?
Where is total timing with vacuum plugged on?
Does the timing change with and with out vacuum?
Are you running ported or non-ported vacuum advance?
What type of gauge are you using?
Where on the engine is the sender?
Have you double checked the temp with second gauge or thermometer?
Does it feel hot? tons of heat radiating off the engine?
Hows it start?
Hows it sound? lifter noisy (yes/no), valves adjusted loose, tight?
The 45 plug is just a hotter heat range plug then the 43's, so it should not cause any problem. The electrode is slightly less insulated to allow the tip to run hotter and help burn off carbon deposits. Its a effective way to keep the plugs cleaner longer.
Joe