scab vender putting a 350 cu in engine in is easy as any any other engine. Just because it has a X- frame it is a little tite on the tranny area. I have a 350 cu. with a 400 tranny and it fits which is just a shade bigger. The only thing is you may have to modify a factory after market one or make your tranny mount which is what I did. You will have Approxmately 5/8" 3/4" if you use the Rams Horm 2 1/2" center dump manifolds. You will also have about 1/2" clearance on the GM. Rebuiltable Fuel Pump.
The Standard Rams Horn and Fuel Pump will give you a little more room to work with without notching the frame areas. One more thing BESURE YOU USE THE RIGHT MOTOR MOUNTS! Good Luck
62Blue
Don