No, a 2WD and a 4WD frame are completely different. A 2WD has a series of bends in it with coil spring rear suspension where-as the 4WD frame is a straight ladder type frame for leaves. I'm building a '63 K20 now and it had a rusty frame too. I bought a 2WD for it's body and considered using it's frame also. Once I had the two frames stripped bare, I could see that wasn't going to happen. I then repaired my 4WD frame instead,
Scott