Negative. I’m run a 283 with TH350.
When I got the Frankentruck the steering column was crudely offset to port the allow them column shifter to clear the headers. There were no inner fenders; the hood had been hacked into a tilt job. I wanted inner fenders and conventional hood hinging , and a properly positioned steering column. It got real tight in the engine bay.
The solution was a double U-joint in the column to get the steering past the header and avoid contact with the inner tub , and a floor shifter for the automatic transmission because there was no room for the arms of the regular shifter- they hit the valve cover iirc.

The column is ‘67 Camaro.