What Tommy is saying is that 1960 and up have a two piece column/steering box. The column shaft can be separated at the "rag joint". The gear box, that is attached to the front steering parts, is a separate unit bolted to the frame.
If your truck has stock steering, you will notice that the column and the gear box are "one piece", NOT separate.
You ask about issues. Of course there are issues with any swap. It's called fabbing. None of the stuff you are doing is bolt on, if that's what you mean. Swapping is all about overcoming the "issues". You don't blast off and buy stuff without knowing what it will take to swap it into whatever truck you have. The only issue is you are jumping topics too much. One post for rear end and start another for steering. Stop jumping around here.
If you have a whole 1984 C10, then you have a whole lot of parts to use for you various swaps including possibly the column. You can put almost any Chevy steering wheel on any Chevy column if you want the look. I really forgot or don't understand what you want the new column for. You can get a floor shift, with a 1950's looking shift lever, for 350 automatic, from Lokar. You could keep the original column and abandon the shift lever and linkage.
When dropping a 350/350 into an AD it's probably advisable to get power steering, brakes, suspension and cooling upgrades because you will no doubt be hot rodding. The IFS will help with some of those. All this is a lot of time, money and work. Welding skills needed, fabrication skills needed, careful workmanship and measuring needed. Solid 1950 frame needed. Don't buy a 6 lug rear end and think you are going to change it to 5 lug. That would be a real big issue.


Right is right, even if everyone is against it, and wrong is wrong, even if everyone is for it. - William Penn