Justin, Most carbs are set with the mixture screw at 1 1/2 turns out from a soft close. Don't twist it tight, just seat it in the housing and back it out 1 1/2 turns. The vacuum gauge won't show much when setting the mixture, you can get just as close by ear and feel. The engine should smooth out when you are close.
The vacuum gauge really helps when setting timing, but once its set, you might need to tweak the mixture again along with the idle speed. I usually set all three at the same time and fine tune them till it feels right.
High vacuum, good idle speed, starts right up, and doesn't burn your eye's, thats a good tune up!
