No, that won't effect the running condition
A couple ideas;
Are you sure the vacuum advance is working? When you open the throttle do you see the distributor turn?
Accelerator pump(s) not working correctly. When you are at partial throttle and nail the peddle do you have a hesitation also?
If not it could be that there is too much wear/slack in the linkages to the accelerator pumps.
Watch the linkage while you open the throttle by hand, does the plunger move with the slightest opening or do you have it off idle before it starts to move.
Take the air filters off, engine not running and look in each carb. How far do you have to move the throttle plate before you see gas squirting in from the accelerator pumps.
If all else fails, richen the idle mixtures and see if that helps. Close each screw 1/4 turn and try it. If not fixed, another 1/4 and adjust idle speed and try again.
