Bill (and Cletis),
If you take out the ignition switch assembly and give the assembly to locksmith, can a key then be made/matched to the cylinder?
A good locksmith could possibly pick the lock and remove it from the assembly but no telling what the labor charge would be.
A locksmith with a master key set can remove the cylinder from the switch. Once he has it out he can remove the tumblers, read them and make a key for it. If he happens to have a stock of tumblers for 50-80 year old GM products he can change the tumblers to fit any key you want.
The hard part is finding a locksmith with the master keys and the tumblers for 50-80 year old vehicles. Most of those items have been sold to hobbyists like me.