Hi Spencer
I wont to put in my chevy 3600 47-51 door latch and striker in my 1952 chevy,opposite than you, the latchs holes are not the same, the 49 ext handle not fit into the 1952 door, the 1949 drive door has the hole for the lock, the 1952 not because this lock is the same push botton.
In summary, don't work without any modification