I'll be going tubeless with the good 16" wheels that I have on the 1954 3104 we are restoring.

However, I've got about 9,000 miles in 9 years on a set of Cooper SRM II LT radials that the Cooper dealer put radial tubes in. I travel mostly highways, over 80% of travel at 60+ MPH (but not fast speeds on curvy roads). These are not low-profile radials - they have a profile similar to original bias ply tires (maybe that results in less side-wall to inner-tube movement/friction?).