Well, first lets talk frame. You will almost definately need to fabricate your motor mounts, transmission crossmember, wiring, etc. Take measurements. Now you need to figure out what motor you are putting in this thing. Are you going for something out of a barracuda, mustang, gto, bel air, etc.? Are you going to have to swap out the axles? How are you going to connect that driveshaft to the rear axle? How do you plan on working with the wiring harness? Are you going to try and connect the truck wiring harness to the car engine, or are you going to put the wiring harness in the truck that came out of the car? Please give us more info. But hey, if you think you are up to the challenge, go for it! I am thinking about putting a 2WD, manual transmission, 12 Valve Cummins Diesel engine in a 1955 Chevy 6400. Good luck!