I know its been done. I've seen two AD trucks at car shows in the area that had Ford motors under the hood.
In both cases I talked with the owners and got a real lifted finger feel from the owners. Neither said it, but my sense were these are Ford guys wanting to fight back.
But then I frequently tell a Mercedes owner I know about how I'm putting a Chevy motor in a Mercedes. I don't own a Mercedes but it does make a good story and he sure doesn't like it.