I have been working out the details myself for my 1950 1/2 ton. I just purchased a 5.3 complete with 4l60 tranny and drive shaft yoke, with 70K for $1,600 from local salvage yard. I also have ordered a complete wiring harness and computer from painless wiring, item 60017 $1,000.
Painless system is complete, replaces factory harness, and requires a hot and ground to operate. Only extra will be a high pressure fuel pump.