When a sbc is located in the "stock" location. That is centered between the frame rails, there is interference with the steering box.
You have not stated your build theme, so it is difficult to know what problems you will run into.
If you are going to use an IFS, the steering can be fabricated to miss the exaust. If you are using a stock axle, the engine can be offset or the steering can be offset. Either way, this swap has been done many times. My first engine swap was in one of these truck; that was almost 40 years ago. I offset the steering at the time.
Do some searches and you will come up with lots of good ideas.
