The general rule of thumb on tapered roller bearings is to tighten the spindle nut firmly (15-20 ft./lbs.), spin the wheel a couple of times, and then back off until the nut turns freely. This squeezes any excess grease out from between the cone and cup. Then tighten the nut until it's barely snug, perhaps 20-30 INCH pounds. If the cotter pin doesn't line up, back off a little.
Jerry