I had issues with bondo over my POR-15... it bubbled up...I didnt wait long enough and it was a bit chilly...
POR-15 recommends you use their products....
I can only imagine the POR was still curing,i.e giving off gasses.
I've painted
over bondo with no ill effects.
I agree with carpoor though, I would save the POR for non-topcoat situations. POR recommend their 'tie coat' (They would!)
I certainly wouldn't use it in exposed bodywork areas and try to overpaint.