differentials are usually offcentered a bit - and if yer talkin 4x4 here [transfer case?] then the front differential is very off center - are you using axles from a 2wd?
running w/ a drive shaft that angles side to side on top of the usual up and down angle wouldn't sound good to me - at the least I'd expect U-joints will not last long!
pictures?

Bill

Moved over to the Passing Lane

"When we tug a single thing in nature, we find it attached to the rest of the world" ~ John Muir
"When we tug a single thing on an old truck, we find it falls off" ~ me
Some TF series details & TF heater pics