If you are looking for easy supercharger, then look at the turbine types such as Paxton, Vortech, procharger, etc vs the positive displacement versions such as magnacharger, eaton, etc. The turbine chargers have the compressor side of a turbo with a gearbox on the input side driven off of the crank pulley.
Using a Turbo on an I6 is not new, I see a large number of 194/230/250/292 turbo exhaust manifolds on Ebay and other web sites, however not the 216 or 235. I am not sure that the 216/235 would have enough oil pressure to make the turbo live.
depending on your compression ratio, you may want to stay relatively low on boost anyway, say between 6 and 12psi unless you are building a boost engine from scratch
In either event, you will want to go with fuel injection over carburation for tuneability.
just my $.02
Scott
