I knew a guy that did a swap like this and he liked it, but he is F**D man. He did this swap in a 76 Chevy Club cab pickup. He later decided he wanted 4WD, and the F**d drivetrain would not permit this crossbreeding, so he then changed back to a 454 and turbo 400 tranny. The latest incarnation I heard he did was swap a 5.9L Cummins drivetrain for the 454.
This proves the theory that with a torch and welder, any swap is possible, but if you figure all the little stuff included in a swap, particularly in a brand A to brand B swap, your time really has to be cheap to make this work.