Kevinski, my concern with using the fan to suck out the air (and fumes) is that the motor on the fan is nothing special and I don't want to risk volatile materials being exposed to the motor. I am hoping (maybe wishfully) that I can avoid blowing dust around by filtering the incoming air and having the booth pretty clean before I start.
Klhansen, did you mean that getting the veloicty of the incoming air DOWN is key? I assume that the low velocity would help minimize the potential to kick up dust. I was not anticipating a plenum but that is a good idea to avoid both high velocity and the potential for a lot of differences in air flow throughout the room. I will probably still use a filter on the intake side of the fan to minimize the amount of dust etc. that otherwie would be influencing the plenum exit filters.
I assume that the wet floor is also to keep dust down.