Put a turbo on it! Go tiny twins, even! In fact, going split manifold or cast iron header makes a huge difference. I was stunned what it did for my 292 in my 78 GMC dump truck. I also installed a pair of 79 Honda CX 500 carbs on it first, which gave it power on the big end. The cast iron headers added another 25% more HP at least after the carb mod.
www.youtube.com/watch?v=obzULioHc64I didn't believe the claims of 20-40% increase from the headers, but I do now! 10 years later, the header still doesn't leak!
The compression is low enough you can turbo that nicely, and the head is re-done so you have the hardened seats. Gee, do it right and they won't know if it's the turbo or the siren! LOL!
Oh, and turn off your A/C when you pull a hill! ;-)