I just completed a power 4 wheel disc brake conversion on my '50 GMC 250 1 ton truck and highly, highly recommend it.
Some of the opposition is likely from the crowd that's not going to come off the hip for the $1000 needed for the conversion, outside of that its a no-brainer - if the ability to quickly stop your truck is a priority. With all the talk around installing 14 bolt rear ends, LS engines, etc you'd think it would be even more popular.
My setup: 14 bolt C&C rear end, 76-78 Eldorado disc calipers (for parking brake) and rotors from 79-87 C20 truck, caliper brackets are available from several vendors, mine came from East Coast Gear Supply, Louisburg, NC.
Front Disc calipers and rotors from 79-87 C20 truck, mounted using brackets from TSM Manufacturing.
https://www.tsmmfg.net/ - can't recommend these guys enough. They have a top quality product and offer great support.
Brake Booster, MC, proportioning valve, with bracket - Performance Parts on Line beat Tuckers price for the same part and its a direct bolt on.
https://www.performanceonline.com/1947-55-CHEVY-GMC-TRUCK-POWER-BRAKE-BOOSTER-KIT/I also installed the remote MC reservoir from POL as a convenience.
The rest of the truck is pretty stock with 261 engine with a few modern upgrades such as; PCV, electronic ignition, modern oil filtration.
Trans is a Saginaw 2 bar with Patrick's shift locator kit.