Not a panel but my 3600 has front glass fenders. The second owner bought it from old farmer's family when he died a few years ago and eventhough it was a sub 40k truck that lived in a barn it was a farm work truck and the fenders were pretty beat up. His easy/cheap button was fiberglass. The paint's pretty good and you really can't they're not metal unless you look underneath. I painted the back side flat black and that along with the normal amount of country dust and mud makes it almost impossible to tell they're not originals. And, if ever damaged it's pretty easy to repair and no rust, ever.
For a few months I thought I'd buy original steel and change them out. Now I don't think I would even if someone donated a free set. My truck is a working, every day (as needed) driver so what's the point.
I'd use glass if price was favorable and never look back.