It seems there's been a lot more questions lately regarding swapping in a 292 where folks would have normally put a 261 or 302. Pull up the rope, I got mine -- 261, that is

but I'm guessing these engines are getting harder to find so folks are naturally turning to more readily available alternatives. Am I reading the tea leaves accurately here?
So what's the consensus -- Is the later straight six a viable option for repowering, say, a Task Force, Advance Design or earlier truck? And is it doable by the average Stovebolter/weekend mechanic ?
If yes to both, then we ought to have some sort of a Tech Tip focusing on it ....
Discussion?