Yes. The size of the tire will determine the length and spacing. I am making a Hitch for a friend and he has a 52 with that same carrier. It has been a challenge to make it so that it works nicely with that carrier, but it worked out great. Personally, I am not real impressed with the 51-59 carrier. Seems kind of unwieldy and no good way to balance the tire on that thin rail when wrestling with getting it up there, but it is what it is.