I have been sold out of the 2100/2101 since the day after Noah landed the Ark, so don't have one to look at.
GUESSING - it appears to be a home-made bowl vent instead of venting the bowl into the air intake. Most of the Carter YF carbs have a 1/4 inch tube coming up into the air intake, and this appears to have been removed and plugged in your picture.
I think I would open the hole into the air intake, and plug the hole to the outside.
Jon.