Yes if you have the correct wheel offset.

When I bought my '65 it had 31/10.5/15 on the rear, utilizing stock Chevy 4x4 rally wheels.....
http://i645.photobucket.com/albums/...Rear%20Fenders%20Nov%202008/100_6793.jpg

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In the Stovebolt Gallery ~~ "The Orange Crate" 1965 C10 SWB Step Side Build Thread

Inspired to be different. Different in a way of my own, not in a way that others strive.