can't say about using them on a pickup, but the reason GM put them on panels and burbs is to counteract the large tall bodies tendency to be pushed around by side winds, can't imagine there'd be a significant advantage on a pickup
"When we tug a single thing in nature, we find it attached to the rest of the world" ~ John Muir "When we tug a single thing on an old truck, we find it falls off" ~ me Some TF series details & TF heater pics