I would recommend not using the stock front strut type mounts if that's what you mean. Don't know what trans, but you may need a "truck" bell housing. I have done this several times using universal cross members for motor and tranny. Easy, cheap and you can mock it up to clear firewall/dizzy/radiator, no sweat. The 350 already has center motor mounts. Install with Carb mounting surface level. The 350 may not have provision for front/corner mount brackets. Some 55.2 3100's were possibly built with the 265 but mostly 5000 series. So if you had a 6 in your truck, the mount is in a little different place than the V8 would have been.