I built my first stroker engine in 1963, a flathead Ford with a 49 Mercury 4" stroke crankshaft, and I've changed strokes up and down several times since then. Just be sure the engine works on paper before you start whittling on the crankshaft. One of my most successful stroke-change engines was a destroked 305 that ended up at 255 cubic inches. That one would run close to 8K RPM on a small Holley 2-barrel carburetor, about 1,000 RPM faster than the guys running 350 Chevy engines on the same carb. Nobody could figure why I could outwind everybody else down the straightaways, and the tech inspectors were too dumb to figure out what I was doing.
Jerry