I have been repairing and building tube equipment for 10+ years. It is like any other hobby: if you are careless, unlucky, or just plain stupid, you can get hurt. You know not to stick your fingers in turning fan blade don't you??? Same concept here. If you read up and understand what you are doing, you'll be fine.
4onthefloor
I have never seen a piece of 50s era consumer electronics with +100uF B+ caps (400V+) but I've never messed with any TVs. The technology for cost effective large electrolytics didn't exist back then. I have heard anecdotes that the 300-400V is more dangerous; supposedly more likely to fibrilate your heart.