Here's a gear calculator
http://www.onlineconversion.com/bigger_tires.htmWith it you can plug in your numbers and see what your different options will do as far as RPM and MPH.
looks like the 0.73 OD on the NV4500 will take you from 45 ish to about 60 mph at 2,500 rpm (with 36"? tires). That seems plenty unless you've got more power and good/better brakes too.
Plug the numbers in and see what you get and what you can live with.
Grigg