That sounds like a good combination. When axles and differentials start to break, is when the traction is increases because of the addition of wider, stickier tires.
I never thought of using fenderwell headers because I live in an area where there is lots of rain in the winter and I didn't think the headers would last. I don't recall seeing any stainless headers being offered in the 70's. It wasn't a major problem cutting and welding the pipes for the 3rd and 4th cylinders because there is plenty of room to do a neat job. There is lots of room for the big block in the 55 to 59 engine compartment.
Bob


55 Cameo 396 TH 400 with overdrive
65 Caliente conv
67 BB Caliente conv
67 Mercury 1 Ton
76 GMC 3/4 ton 454ci
84 Buick Turbo Regal