I wouldnot get too wild & make a large excursion. About .002 smaller is all you need. I also wouldn't mess with it much till I got settled in. Ive driven cars out to Co. for 60 years from Mo. & never had a problem with fuel mixtures. Of coarce you do loose some power. Ive been up & down Pikes peak about a dozen times the first time in a 53 ford with a flathead v-8. They used to have places to pull off with a water hose you poured water over your rad. to cool it down. Co. is my favorite vacation spot. The scenery is spectacular & the people are friendly.