I have a Dana 80, not Dodge, with the 6 lug Budd bolt pattern, and it has 22.5" wheels on it right now.
I doubt but am not sure if you could bolt this big caliper bracket in place of the dodge brakes, or make a new flange to weld to the axle tube, the hubs may interchange, but not sure on that either.
But if that is your goal by the time you find another one of these Dana 80's with 6 lug Budd hubs you may as well use it and leave the Doge stuff alone.
Grigg