As all have said, it's your truck. But to answer your question, I suspect the less flashy and closer to an original color, the better the resale value.
If you're unsure, I'd suggest first finding a photo shop volunteer to create some mock-ups. I did that and eliminated a number of combinations I was sure would look super - they didn't. Then I'd find a plastic model and paint it the exact colors you plan to use. This helped me confirm I made the right final choice. Just got it back a few weeks ago, guess what - surprise, it looks just like the model!
I saw one for sale recently that had the combo I was certain would be killer early on - ouch - fugly, glad I took the time to keep testing combo's out.
The color combo you are thinking of I personally wouldn't like. However, there was one a year ago with the reverse of that but solid (non-metallic) - Medium blue fenders and wheels, creamy white all else. Totally not factory or original. Never sold on eBay at an asking price of $25,000. Sold shortly thereafter at Barrett Jackson for $40k.
Personally I like the two tone look, but with subtle shade variations - I went with Pepper White Cab/Bed and Medium tan fenders. I think it looks very period correct if not factory original. I've also seen some light grey with medium grey fenders that looked good as well.
Good luck, have fun.
