A factory 400 would have steam holes drilled in the block and heads. If other heads are to be used, steam holes would have to be drilled to match up with the block or it will overheat. I'm not sure if 400 SB's are externally balanced but if you use the balancer and flex plate from the donor vehicle you should not have any problems.
Fred


1956 3100 Pickup/Red/350/3sp OD/PS/Disc Brakes
1957 Bel Air Sport Coupe/Red/355/TH350/PS/Disc Brakes
2017 Silverado LT Single Cab SB/Black/5.3/6 Speed Trans
1947 Willys CJ2A w/F-Head engine