What are you calling a larger truck? 1955 and up 3 ton with a V8 came with a 4 barrel. GMC used a Holley 4000. Chev a 4GC Rochester. If you are talking about a 6 cy, a 4 barrel is the absolute largest you can use unless its a really wild engine. 4 barrels are a lot less hassle than multiple carb setups.