I'm using an Offy dual single bbl intake with Holley Model 1904 carbs.
Hot Rod Lincoln (Jerry) suggests using carbs for the 216, and modifying the manifold for the smaller bolt pattern. For a street driven truck, this would really be the hot setup, as it will help eliminate many of the problems that multiple carburation brings with it (like the off idle dead spot).
Jerry and Jon (Carbking) are the best 2 to ask for advice, both are very knowlegable in this area.